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The monologue, the desk, the guests, the band. The ingredients of the late night TV formula are familiar, yet fickle. Get them just right and a show can last for decades. Make one mistake and your career is over – fast. In this episode, we explore the alchemy that turns a late night TV show into ratings and social media gold. Jimmy Kimmel, Desus & Mero, David Letterman producer and co-creator of The Daily Show co-creator Madeleine Smithberg, Tonight Show regular Byron Allen and more give us insights into the hardships of mastering the formula perfected by Johnny Carson.